How Coffee Interacts with Aminoglycoside Antibiotics

Caffeine belongs to the methylxanthine family. Besides keeping you awake, caffeine can modestly increase heart rate, blood pressure, and urine output, and in high doses it may contribute to dehydration. Coffee is also rich in polyphenols and other bioactive compounds that can act as antioxidants and may influence how drugs move in the body or behave at the bacterial cell wall.

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